Scientist - DMPK Aurigene Oncology Limited. (a Dr. Reddy's Subsidiary)

6.0 - 10.0 years

7 - 12 Lacs

bengaluru

Work from Office

Key Responsibilities: Conduct in-vitro ADME experiments (metabolic stability, CYP inhibition, MBI/TDI, PPB, blood/plasma stability, etc.) and interpret results. Operate and maintain various LC-MS/MS systems for bioanalysis of in-vitro ADME samples. Review in-vitro ADME data and coordinate with project team members. Prepare and review SOPs, study protocols, and reports for regulatory submissions. Ensure compliance with GLP and internal quality standards. Strong understanding of drug metabolism and pharmacokinetics. Proficiency in MS Office and GraphPad Prism. Excellent communication, interpersonal skills, and ability to work in a team.

Posted 2 weeks ago

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Pharmacologist PI Health Sciences Ltd

6.0 - 10.0 years

0 Lacs

hyderabad, telangana

On-site

As a Research Scientist - In Vitro ADME, your primary role is to generate high-quality and reproducible in-vitro ADME data to support medicinal chemistry and discovery biology teams in optimizing molecular properties. This involves robust ADME assay execution, scientific interpretation, innovation in assay methodologies, and effective cross-functional collaboration to accelerate hit-to-lead and lead optimization programs. Key Responsibilities: - Provide strategic ADME insights to Medicinal Chemistry and Biology for compound prioritization. - Influence project direction by interpreting trends in clearance, permeability, solubility, DDI risk, and transporter interactions. - Contribute to defin...

Posted 1 month ago

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Senior Associate Scientist Syngene

3.0 - 8.0 years

3 - 8 Lacs

Hyderabad, Bengaluru

Work from Office

Role & responsibilities Extensive experience in planning metabolic stability, CYP inhibition assays Design and execute in-vitro Single point inhibition, reversible CYPIC50 inhibition and TDI-IC50 shift assay with human liver microsomes. Seamless coordination with BA-DMPK group to design in-vitro CYP inhibition studies. Preparation of SOPs and EOPs. Reporting of executed studies without any noncompliance. Reporting of study results clearly in the cross functional scientific meetings. Follow environment, health, and safety (EHS) requirements at all times in the workplace ensuring individual and lab/plant safety. Ensure environment, health, and safety (EHS) measures are imparted via training an...

Posted 5 months ago

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ADME Syngene

2.0 - 7.0 years

3 - 8 Lacs

Hyderabad, Bengaluru

Work from Office

Job Title: ADME Scientist Job Location: Bangalore/Hyderabad Department: Discovery Biology About Syngene Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, imp...

Posted 5 months ago

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