Bsc (Chemistry) Fresher

Quality Control (QC) Wet Lab Chemist — Job Profile

# Overview

A QC wet lab chemist ensures raw materials, in-process samples, and finished products meet predefined specifications through laboratory testing, documentation, and compliance with quality and safety systems. The role is common in pharmaceuticals, specialty chemicals manufacturing.

## Core Responsibilities

- Perform routine and non-routine wet chemistry tests: titrations (acid-base, redox, complexometric), pH, conductivity, viscosity, moisture (Karl Fischer), chloride/sulfate by argentometric/gravimetric, hardness, ash, loss on drying, refractive index, melting point, etc.

- Conduct instrumental analyses commonly used alongside wet chemistry: UV-Vis spectrophotometry, FTIR, TOC; often exposure to pharma/chemicals.

- Sample handling: receipt, identification, and representative sampling of raw materials, intermediates, finished product, stability, and environmental/utility samples (e.g., purified water).

- Method execution and verification: follow pharmacopeial (IP, USP, BP, EP) and validated in-house methods; assist in method transfer and robustness checks.

- Data integrity and documentation: contemporaneous recording in controlled notebooks/eLIMS, calculations, CoA generation, deviations/OOS/OOT investigations, and change controls.

- Equipment management: daily checks, calibrations, basic troubleshooting, and preventive maintenance coordination for balances, pH meters, KF titrators, burettes, ovens, muffle furnaces, viscometers, UV-Vis, FTIR.

- Quality systems: adhere to GLP, GDP, cGMP; participate in internal/external audits; implement CAPA and continuous improvement.

- Safety and housekeeping: chemical hygiene, PPE, MSDS/SDS use, waste segregation, fume hood practices, 5S.

- Cross-functional support: interface with production, QA, R&D/ADL for investigations, specification setting, and process improvements.

## Typical Day in the Lab

- Calibrate pH meter/balances; standardize titrants (e.g., NaOH, HCl, AgNO3).

- Analyze queued samples; compute results; peer review and submit for QA disposition.

- Document any abnormalities; raise incident or deviation if required.

- Maintain inventory of reagents/standards; prepare fresh reagents/standards as per SOP.

- Verify logbooks/equipment usage logs, and close the day with status updates.

## Key Skills and Competencies

- Technical: strong wet chemistry, titration theory, solution prep and standardization and uncertainty calculations, pharmacopeial methods, familiarity with UV-Vis/FTIR/KF.

- Quality and compliance: GLP, GDP, cGMP, data integrity (ALCOA+), qualification/validation basics (IQ/OQ/PQ), OOS/OOT/OOT trending, stability studies.

- Digital: LIMS/eLIMS, Excel for calculations and trending, basic instrument software.

- Soft skills: attention to detail, time management under TAT pressure, teamwork, clear documentation and communication, problem-solving during investigations.

- Safety: chemical risk assessment, handling corrosives/oxidizers/solvents, spill response, waste management.

## Educational Requirements

- BSc/MSc in Chemistry, Analytical Chemistry, or related (Biochemistry/Pharmaceutical Chemistry).

- Freshers can enter as trainee QC chemists; internships or 3–6 months industrial training are advantages.

- Certifications helpful: cGMP/GLP, data integrity, pharmacopeial methods, EHS.

## Common Tests and Methods (Wet Lab Focus)

- Titrations: acid-base (potentiometric/manual), redox (iodometry/permanganometry), complexometric (EDTA for hardness/metals), precipitation (Mohr/Volhard).

- Physical tests: pH, conductivity, specific gravity/density, viscosity (Brookfield/Ubbelohde), melting/softening point, residue on ignition/ash, loss on drying.

- Moisture: volumetric and coulometric Karl Fischer.

- Spectroscopy: UV-Vis assay/impurities, FTIR identification.

- Water/utility: pH, cond…

Job Type: Full-time

Pay: ₹12,000.00 - ₹15,000.00 per month

Work Location: In person