Industrial Post-Doctoral Fellow-HPLC Method Development (Protein Biologics) About Mynvax Mynvax is a clinical-stage vaccine biotechnology company headquartered in Bangalore, India, developing novel, recombinant, and thermostable vaccines against respiratory viral infections, including influenza and RSV. With a pipeline of promising candidates and multiple ongoing collaborations, Mynvax offers a unique opportunity to work at the cutting edge of vaccine development. Role Design, develop, and optimize HPLC/UPLC methods (e.g., SEC, RP-HPLC, IEX, HIC) for protein characterization, including purity, aggregation, charge variants, and stability. Conduct protein analysis using HPLC and orthogonal techniques for in-process and final DS samples. Interpret results, troubleshooting analytical challenges, and ensure data quality and integrity. Prepare analytical protocols, reports, and SOPs, and contribute to method development and qualification. Collaborate with upstream, downstream, and formulation development teams. Support regulatory submissions with high-quality analytical documentation. Required Qualifications Ph.D. in Biophysics, Biochemistry, Analytical Chemistry, Biotechnology, or a related field. Hands-on experience in HPLC method development for proteins (during Ph.D. or postdoc). Basic understanding of protein structure, behavior, and physicochemical properties. Familiarity with HPLC data acquisition and analysis software (e.g., Openlab CDS, Empower, ChemStation). Desirable Skills Knowledge of ICH Q2/WHO guidelines for analytical method validation. Experience with protein biologics, vaccine antigens, or biosimilar analytics. Familiarity with other techniques such as CE, SDS-PAGE, Western blotting, or ELISA. What Mynvax offers: A stimulating industrial research environment with real-world impact. Exposure to state-of-the-art technologies and multidisciplinary collaboration. Mentorship and professional development support from experienced scientists. Full-time salary and benefits include health coverage, generous leave package, and statutory entitlements. Location: Bangalore, India Company: Mynvax Private Limited Position Type: Full-Time | Fixed Term (12-24 months, extendable) Start Date: Immediate Compensation: Competitive salary with full-time employee benefits How to apply: Email your CV and a brief cover letter to careers@mynvax.com Subject line: "Post-Doctoral Fellow-HPLC Application" Apply on LinkedIn: Post-Doctoral Fellow-HPLC Application
Mynvax is a clinical-stage vaccine biotechnology company headquartered in Bangalore, India, developing novel, recombinant, and thermostable vaccines against respiratory viral infections, including influenza and RSV. With a pipeline of promising candidates and multiple ongoing collaborations, Mynvax offers a unique opportunity to work at the cutting edge of vaccine development. Role Perform gene cloning using various strategies including restriction/ligation, Gibson Assembly, and Golden Gate. Carry out site-directed mutagenesis and construct verification. Design and run PCR assays for amplification and screening. Prepare and submit samples for Sanger sequencing; analyze sequencing results. Express recombinant proteins in E. coli or other expression systems. Run SDS-PAGE and Western blotting for protein expression and analysis. Maintain accurate and detailed lab records; ensure reproducibility and quality of experimental data. Collaborate with team members involved in antigen production and vaccine R&D. Required Qualifications M.Sc. or M.Tech. in Molecular Biology, Biotechnology, Microbiology, or related field. 0-3 years of hands-on experience in molecular biology techniques. Experience with cloning methods including restriction/ligation, Gibson Assembly, Golden Gate, and site-directed mutagenesis. Basic understanding of recombinant protein expression workflows. Familiarity with PCR, gel electrophoresis, and gel-based detection methods. Desirable Skills Experience in bacterial transformation, plasmid preparation, and cloning troubleshooting. Experience with mammalian and insect cells expression systems. Knowledge of protein purification techniques such as Ni-NTA affinity chromatography. Familiarity with software tools for primer design and sequence analysis. What Mynvax offers: A dynamic research environment with exposure to cutting-edge vaccine development. Mentoring by senior scientists and opportunity for career growth. Competitive salary and full-time employment benefits. Location: Bangalore, India Company: Mynvax Private Limited Position Type: Full-Time Start Date: Immediate How to Apply: Email your CV and a brief cover letter to careers@mynvax.com Subject line: "Application-Research Associate Molecular Biology" Apply on LinkedIn: Research Associate-Molecular Biology
Research Associate, Cell Culture and Bioassays About Mynvax Mynvax is a clinical-stage vaccine biotechnology company headquartered in Bangalore, India, developing novel, recombinant, and thermostable vaccines against respiratory viral infections, including influenza and RSV. With a pipeline of promising candidates and multiple ongoing collaborations, Mynvax offers a unique opportunity to work at the cutting edge of vaccine development. Role Maintain and passage mammalian cell lines under sterile conditions. Support in vitro bioassays such as ELISA, virus neutralization assays, and cytopathic effect-based assays. Perform RNA isolation, cDNA synthesis, and qPCR for viral load estimation. Assist in the preparation and handling of BSL-2 viruses under appropriate biosafety protocols. Process animal sera or tissue samples for immunological analysis. Maintain laboratory notebooks and electronic records with high attention to detail. Assist with assay optimization, reagent preparation, and documentation for preclinical studies. Ensure compliance with biosafety and quality standards during laboratory operations. Required Qualifications M.Sc. or M. Tech in biotechnology, microbiology, immunology, or related life science fields. 0-3 years of hands-on laboratory experience in academic or industrial settings. Familiarity with mammalian cell culture, ELISA, and virus-based neutralization assays. Knowledge of BSL-2 biosafety practices and handling of infectious materials. Good understanding of basic laboratory techniques and experimental design. Desirable Skills Experience with in vivo sample collection or processing from preclinical models. Exposure to data analysis tools and statistical interpretation of assay results. Prior work in a regulated or GLP/GMP-compliant environment. What Mynvax offers: A dynamic research environment with exposure to cutting-edge vaccine development. Training and mentorship in immunology, virology, and preclinical research. Collaborative environment with growth opportunities and skill development. Competitive salary and full-time employment benefits.
Mynvax is a biotechnology company focused on the discovery, development, and scalable manufacturing of thermostable recombinant vaccines against respiratory and emerging viral infections. The company collaborates closely with leading academic and translational partners including the Indian Institute of Science, THSTI, and global R&D groups. Role Lead upstream process development for recombinant protein and vaccine antigen production using insect (Sf9, Sf21) & mammalian (CHO) cells. Plan, design, and execute experiments for media/feed optimization, infection/transfection kinetics, and process scale-up (1-50 L). Supervise and mentor a team of 4-5 Research Associates/Senior Research Associates to ensure smooth lab and pilot-scale operations. Ensure adherence to aseptic and cleanroom practices, GLP/GMP guidelines, and biosafety regulations. Review and approve experimental protocols, batch records, and process documentation. Collaborate cross-functionally with downstream, analytical, and QA/QC teams for process integration and technology transfer. Participate in troubleshooting, root cause analysis, and CAPA implementation for upstream-related deviations. Prepare detailed technical reports, development summaries, and contribute to regulatory documentation and IND/IMPD filings. Drive innovation in upstream process optimization using statistical design tools (DoE), PAT, and bioreactor data analytics. Plan resource utilization, equipment scheduling, and inventory management for the upstream lab. Required Qualifications and skills Ph.D. or MTech/M.Sc. in Biotechnology, Biochemical Engineering, or related life sciences discipline. 7-12 years of industrial experience in cell culture-based process development and scale-up for recombinant proteins or vaccines. Strong hands-on experience with insect cell culture (baculovirus/Sf9 systems) and mammalian cell lines (CHO). Experience operating and optimizing bioreactors (1-50 L) and familiarity with bioreactor control systems (Applikon, Sartorius, etc.). Proven ability to lead and mentor teams in a fast-paced R&D environment. Excellent understanding of aseptic techniques, bioprocess scale-up, and upstream-downstream process interfaces. Strong project management, documentation, and presentation skills. Ability to independently plan, execute, and deliver on project timelines. Desirable Skills Exposure to GMP manufacturing or tech transfer environments. Experience with statistical design tools (DoE, JMP, Minitab) and PAT implementation. Knowledge of vaccine development workflows and regulatory documentation requirements (IND/IMPD). Familiarity with continuous processing or high-cell-density culture systems. Reporting to Head-Preclinical R&D
Mynvax is a biotechnology company focused on the discovery, development, and scalable manufacturing of thermostable recombinant vaccines against respiratory and emerging viral infections. The company collaborates closely with leading academic and translational partners including the Indian Institute of Science, Bangalore. Role Execute and optimize cell culture processes using E. coli and insect cell systems (Sf9, High Five, etc.) and baculovirus expression workflows. Operate and maintain bioreactors (1-50 L scale) for process development and optimization studies. Perform cell revival, maintenance and prepare cell banks. Perform media and feed optimization, infection kinetics, and yield analysis for recombinant protein expression. Adhere to aseptic and cleanroom procedures under GLP/GMP-like conditions. Maintain accurate batch records, logbooks, and SOP documentation. Support scale-up, process characterization, and tech transfer to pilot/manufacturing teams. Coordinate with downstream, analytical, and QA/QC teams to ensure data integrity and process consistency. Participate in equipment qualification, calibration, and preventive maintenance activities. Present experimental findings in team meetings and contribute to technical reports and publications. Required Qualifications M.Sc. / M. Tech. / B.E. / B. Tech in Biotechnology, Biochemical Engineering, or a related life science discipline. 3-5 years of hands-on experience in cell culture and bioreactor-based process development. Familiarity with handling insect cell expression systems is essential. Experience with bioreactor control systems (Sartorius, Minfors or equivalent) and data analysis software. Experience handling 1-5L glass bioreactors. Strong understanding of aseptic techniques, biosafety, and cleanroom practices. Knowledge of upstream process scale-up principles and basic downstream interface requirements. Excellent documentation, analytical, and communication skills. Ability to work collaboratively in a fast-paced RD environment. Desirable Skills Exposure to insect cell culture systems (Sf9, Sf21) for recombinant protein production. Handling of single-use bioreactors (50L and 200L scale) Basic knowledge of DoE-based optimization and process analytical technologies (PAT). Familiarity with GMP documentation and tech transfer dossiers. Prior experience in vaccine, biologics, or biosimilar development environments. Reporting to Manager-Upstream Process Development