Scientist - ADC DMPK

As an experienced candidate with a background in M. Pharm (Pharmacology / Pharmaceutical Analysis) / M.Sc. (Biochemistry / Pharmaceutical Chemistry) with 11-14 years or Ph.D. with 2-5 years of experience in large molecule/ADC PK and bioanalysis, Antibody Drug Conjugate characterization and bioanalysis, mass spectrometry-HRMS, Q-TOF & Triple quad, you will play a crucial role in the following responsibilities: - Expertly design and execute DMPK studies to support antibody-drug conjugate (ADC) and monoclonal antibody (mAb) programs, from discovery through IND-enabling stages. - Possess extensive experience in quantification of biologics including antibodies, therapeutic proteins, ADCs, and peptides using LC-MS/MS, MSD, and ELISA platforms. - Proficiency in utilizing advanced bioinformatics tools such as BioPharma Finder, MaxQuant, Spectronaut, and other relevant analytical software. - Skillfully apply innovative techniques for function-based identification and selection of ADC and mAb lead candidates, emphasizing DMPK profiling to ensure safe and effective therapeutic development. - Capable of interpreting complex DMPK data and providing actionable insights to cross-functional project teams. - Actively represent DMPK functions in internal and external meetings, promoting collaboration and strategic alignment. - Collaborate closely with cross-functional departments to tackle ADC-related challenges and provide integrated solutions from target validation to IND submission. - Take accountability for authoring and reviewing SOPs, study protocols, reports, and regulatory documentation to support both GLP and non-GLP studies. - Possess a strong foundational knowledge of DMPK principles, including PK/PD, toxicology, and translational sciences. Demonstrate capabilities in communication, innovation, and team leadership. The above responsibilities outline the critical role you will play in the successful development of DMPK studies within the organization.,