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Executive

2 - 7 years

3 - 8 Lacs

hyderabad bengaluru mumbai (all areas)

Posted:7 hours ago| Platform: Naukri logo

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Skills Required

biologics upstream mammalian cell culture

Work Mode

Work from Office

Job Type

Full Time

Job Description

Bioreactor Operations (50 L Bioreactor)

  • Bag installation and integrity check.
  • Installation and calibration of sensors (pH, DO, CO).
  • Probe calibration and verification.
  • Aseptic media charge and handling.
  • Aseptic inoculation procedures.
  • Aseptic feed addition during culture.
  • Aseptic sampling from fermenter culture.

Handling of Seed stage equipments

  • Shaker incubator operations .
  • Biosafety cabinet operations .
  • Wave bioreactor equipment’s handling

Media Preparation

  • Preparation of media for mammalian and microbial cell culture under aseptic conditions.

In-Process Quality Control (IPQC) Equipment Handling

  • Automated cell counters (e.g., Benchmen Counter, Roche, or equivalent).
  • Metabolite analyser’s (e.g., Cedex, Siemens, Radiometer).
  • Osmometer operation.
  • Microscope handling for cell observation.
  • Centrifuge operation.
  • Depth filtration skid operations .

Online Documentation

  • Real-time documentation as per

    ICH Q7

    guidelines.
  • Knowledge of

    cGMP compliance

    .
  • Facility maintenance and audit readiness.

Documentation & Protocol Preparation

  • Batch Manufacturing Record (BMR) preparation.
  • Standard Operating Procedures (SOP) drafting.
  • Qualification protocol preparation (SLIA, URS, QRA, OQ).

Autoclave Operation

  • Sterilization of media, equipment, and accessories as per validated cycles.

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