23 Chemical Synthesis Jobs

As a Team Member in Chemical Research & Development at the Research & Development department, specifically in the Peptide Synthesis sub-department, your primary role is to perform chemical synthesis of molecules. This involves process development, process validation, and transferring the processes to production units. Your responsibilities include conducting literature searches, collecting MSDS, performing lab experiments, documenting experimental results, and interpreting spectral data. You will also be responsible for maintaining various documents such as patents, literature, and analytical reports. Collaborating with analytical chemists and DQA on analytical results and methods is an essential part of the role. To ensure the smooth functioning of the lab, you will need to account for chemical usage, availability of raw materials, and perform calibration of lab equipment like weighing balance, pH meter, and driers. Keeping track of regular solvents, reagents, and managing effluent generation from lab experiments are also part of your duties. In addition, you will be required to perform Manual Solid Phase Peptide Synthesis of Peptides on various scales, ranging from medium to commercial scale with minimal supervision. This includes purification of solid phase products, CGMP activities, synthesis of impurities, and degradation impurity standards for analytical method development and validation. Safety awareness and implementation are crucial aspects of this role, and you must strictly adhere to Good Laboratory Practices and Laboratory Safety Norms. Continuous learning and staying updated with industry trends are essential for success in this position. To qualify for this role, you should have an M.Sc. in Organic Chemistry and a minimum of 2 years of experience in the R&D Department of an API manufacturing company. Preferred qualifications include 6 years of experience and knowledge of Process R&D and scale-up processes. In terms of competencies, you should have a strong understanding of coupling reagents, documentation, GLP, safety compliances, plant scale-up, solid phase synthesis, solution phase synthesis, and purification. Behavioral competencies such as results orientation, customer centricity, collaboration & teamwork, problem-solving, planning, and communication are also essential for this role. Continuous learning and professional development are encouraged to excel in this position.,

Develop the scientific & strategic direction of the synthesis research business, overseeing drug discovery initiatives, managing research teams, ensuring the effective administration & growth. Required Candidate profile Ph.D. in Chemistry with 20+ years in CRO/ process development/synthesis with a strong flair of senior/top research leadership role would be an ideal fit. Willing to work at the lab and be a mentor. Perks and benefits Best of CTC, additional perks and benefits

Plan and conduct multi-step organic syntheses to develop novel molecules.Work closely with cross-functional teams, including medicinal chemists,biologists, and analytical scientists to advance drug discovery projects. Required Candidate profile - Experience in medicinal chemistry or CRO environment, preferably in drug discovery, or custom synthesis. - Proficiency in synthetic organic chemistry.

Looking Chemist for Bauxite,iron,coal & Coke testing for world's leading testing & Certification company,NABL , 17025 lab having experience in ICP OES Job Summary: Provide expertise in chemical analysis and research to contribute to the development and improvement of products and processes. Conduct experiments, analyze results, and interpret data to draw conclusions and make recommendations. Ensure compliance with regulatory standards and safety protocols. Key Responsibilities: Perform chemical synthesis, purification, and characterization of compounds. Use analytical techniques such as spectroscopy, chromatography, and mass spectrometry for qualitative and quantitative analysis. Document experimental procedures, results, and findings accurately. Collaborate with multidisciplinary teams to achieve project goals. Stay current with scientific literature and advancements in the field. Maintain laboratory equipment and ensure proper calibration and operation.

Role & responsibilities Expertise in carrying out Multi-step synthesis of organic molecules from milligram to multi-gram scales and their characterization. Responsible for the development efficient synthetic process, which leads to better yields and quality of the product, with less cycle time and cost. Capturing proper learning of the project & would be responsible for maintaining the confidentiality of the project as per the IPR guidelines. Scaling up of process and technology transfer from lab to plant and trouble shooting at the time of scale up. Interpretation of analytical reports like HPLC, GC, NMR, LCMS, IR, GCMS. Knowledge of designing route of synthesis for target molecule. Carried out experiments in laboratory and optimize process in terms of Regulatory Affairs (RA), Safety, cost and time effectiveness. Strong knowledge on process validation in laboratory and demonstration in plants. Adept at preparing documents like Technology transfer document (TTD), Process development report (PDR), presentations and reports for review meetings. Process validation and optimization with QBD. Preparing documents like Solubility chart, Material balance, Green card, Hold time study, Details of process, MSD. Literature search .through Sci-finder and Reaxys Ability to handle linear and parallel multi-step organic synthesis Experienced with purification techniques like thin layer & column chromatography, Crystallization and distillations. Structural elucidation through NMR (1H, 13C), IR, Mass (LC/MS, GC/MS). Good Co ordination with Cross functional teams as well as team mates. Accurate record keeping in laboratory notebook (LNB) and (ELN).

Looking Chemist for Metals and Minerals testing for world's leading testing & Certification company,NABL , 17025 lab having experience in ICP OES Job Summary: Provide expertise in chemical analysis and research to contribute to the development and improvement of products and processes. Conduct experiments, analyze results, and interpret data to draw conclusions and make recommendations. Ensure compliance with regulatory standards and safety protocols. Key Responsibilities: Perform chemical synthesis, purification, and characterization of compounds. Use analytical techniques such as spectroscopy, chromatography, and mass spectrometry for qualitative and quantitative analysis. Document experimental procedures, results, and findings accurately. Collaborate with multidisciplinary teams to achieve project goals. Stay current with scientific literature and advancements in the field. Maintain laboratory equipment and ensure proper calibration and operation.

Role & responsibilities Process Development: Conduct research and design experiments to develop and optimize synthetic routes for API molecules. Perform literature searches for identified API molecules to determine synthesis routes, polymorphs, and analytical methods. Conduct experimental trials to assess feasibility and optimize designed synthetic routes for API molecules. Documentation: Record all experiments in the laboratory notebook (LNB) and maintain corresponding analytical data in organized folders. Design synthetic routes for the synthesis and isolation of impurities and reference standards. Ensure all documentation meets Good Manufacturing Practices (GMP) and regulatory standards. Safety and Compliance: Adhere to all safety protocols and ensure a safe working environment in the laboratory. Develop non-infringing synthetic processes based on literature, raw material availability, and polymorph studies. Stay up-to-date with industry trends, regulatory guidelines, and advancements in chemical synthesis and analytical techniques.Team Collaboration: Plan daily activities for team members, focusing on feasibility studies, process optimization, and laboratory validation. Work closely with the Analytical Research and Development (ARD) team on method development, in-process testing, and reference standards qualification. Qualifications: Education: MSc/BSc in Organic Chemistry, Experience: Minimum of 3-5 years of experience in process development and optimization in the pharmaceutical or bulk drug industry. Skills: Strong knowledge of synthetic organic chemistry and process chemistry. Proficiency in using and interpreting data from analytical instruments. Excellent problem-solving skills and attention to detail. EZective communication and teamwork skills. Ability to work independently and manage multiple projects simultaneously. Preferred candidate profile We are looking for a talented and driven R&D Chemist to join our team. The successful candidate will be responsible for developing and optimizing chemical processes for synthesizing active pharmaceutical ingredients (APIs). This role requires a strong background in synthetic organic chemistry, process development, and scale-up techniques. The R&D Chemist will collaborate with cross-functional teams to ensure the smooth transition of processes from the lab to full-scale production. Perks and benefits

Role & responsibilities Process Development: Conduct research and design experiments to develop and optimize synthetic routes for API molecules. Perform literature searches for identified API molecules to determine synthesis routes, polymorphs, and analytical methods. Conduct experimental trials to assess feasibility and optimize designed synthetic routes for API molecules. Documentation: Record all experiments in the laboratory notebook (LNB) and maintain corresponding analytical data in organized folders. Design synthetic routes for the synthesis and isolation of impurities and reference standards. Ensure all documentation meets Good Manufacturing Practices (GMP) and regulatory standards. Safety and Compliance: Adhere to all safety protocols and ensure a safe working environment in the laboratory. Develop non-infringing synthetic processes based on literature, raw material availability, and polymorph studies. Stay up-to-date with industry trends, regulatory guidelines, and advancements in chemical synthesis and analytical techniques.Team Collaboration: Plan daily activities for team members, focusing on feasibility studies, process optimization, and laboratory validation. Work closely with the Analytical Research and Development (ARD) team on method development, in-process testing, and reference standards qualification. Qualifications: Education: MSc/BSc in Organic Chemistry, Experience: Fresher or 1-2 years experience in process development and optimization in the pharmaceutical or bulk drug industry. Skills: Strong knowledge of synthetic organic chemistry and process chemistry. Proficiency in using and interpreting data from analytical instruments. Excellent problem-solving skills and attention to detail. Effective communication and teamwork skills. Ability to work independently and manage multiple projects simultaneously. Preferred candidate profile We are looking for a talented and driven junior R&D Associate to join our team. The successful candidate will be responsible for developing and optimizing chemical processes for synthesizing active pharmaceutical ingredients (APIs). This role requires a strong background in synthetic organic chemistry, process development, and scale-up techniques. The R&D Chemist will collaborate with cross-functional teams to ensure the smooth transition of processes from the lab to full-scale production. Perks and benefits

About Us Morepen Proprietary Drug Research Pvt. Ltd. (MPDRPL) is a dynamic pharmaceutical R&D organization committed to developing high-quality, affordable generic and novel products for global markets. With a focus on innovation and regulatory compliance, we work in the area of ANDA, NCEs, 50b2, API development and novel polymorphs. Job Roles & Responsibilities Design and optimize Route of Synthesis (RoS) for novel medicinal drugs. Synthesize and purify medicinal compounds using advanced laboratory techniques. Conduct laboratory experiments to test the efficacy and safety of synthesized compounds. Analyse data from various analytical techniques to assess compound quality and properties. Improve the physicochemical properties of existing drugs to enhance performance and stability. Collaborate with other scientists and departments to advance drug development projects. Follow strict health and safety guidelines to ensure a safe working environment. Review and interpret the structure and purity of chemical compounds using modern analytical tools. Knowledge & Experience Bachelors in Medicinal Chemistry with Masters in Medicinal Chemistry, Organic Chemistry, or a related field. With M.Sc. (2 to 4 years of Experience) At least 2 years of hands-on experience in chemical synthesis within a pharmaceutical or biotech setting. Proficiency in modern synthetic techniques and analytical methods (e.g., NMR, HPLC, MS). strong problem-solving skills and the ability to design efficient synthetic routes. Excellent laboratory skills, including safe handling of chemicals and operation of laboratory equipment. Ability to work collaboratively in a team-oriented environment. Excellent written and verbal communication skills. Detail-oriented with strong organizational skills. Commitment to continuous learning and staying current with scientific advancements. Why Join MPDRPL? Be part of an organization driving cost-effective global healthcare solutions . Work on end-to-end projects from concept to market. Collaborate with experts across departments in a quality-driven, innovation-centric environment . Access to modern formulation laboratories and pilot-scale facilities. Competitive compensation with performance-linked incentives . Professional development and career advancement opportunities . Comprehensive employee benefits including healthcare and retirement plans .

Job Title: Research Scientist- Organic Synthesis & Natural Extraction Company: Gait Naurish (I) Ltd. Location: R&D Centre, Sector 155, Noida (NCR), India Employment Type: Full-time, On-site Reporting To: Head- R&D (Food Chemicals) 1. Role Overview Gait Naurish (I) Ltd. seeks a hands-on Research Scientist to develop new food-grade favour chemicals and bio-based extracts. You will combine deep expertise in organic synthesis with practical know-how in natural-product extraction, driving projects from lab bench through pilot scale and tech-transfer to manufacturing. 2. Key Responsibilities & Tasks Design & Execution of Synthetic Routes (50%) Responsible for designing and executing synthetic routes for flavour molecules, sweeteners, and aroma compounds. Tasks include patent and literature scouting, route selection and DoE (Design of Experiments), performing lab-scale reactions (ranging from 5 g to 1 kg), and purification through distillation, column chromatography, and crystallization. Natural Extraction & Isolation of Bio-actives (30%) Work involves extraction and isolation of bio-active compounds such as citrus flavonoids and essential oil fractions using solvent extraction, supercritical CO, and enzyme-assisted techniques. The goal is to optimize yield, selectivity, and color, while also generating data for scale-up and solvent recovery balance. Documentation & Compliance (15%) Responsible for drafting SOPs, batch records, and risk assessments. Ensure compliance with regulatory standards such as FSSAI, FAMI-QS, REACH, and ISO 9001. Cross-functional Collaboration & Mentoring (5%) Coordinate with Production, Quality Control, and Marketing teams. Also involves training and mentoring junior chemists and interns. Time allocations are indicative and may shift with project priorities. 3. Required Qualifications Education B.Sc. Chemistry (Honours) and M.Sc. Organic / Applied / Industrial Chemistry. Experience 1-3 years of hands-on R&D in both synthetic organic chemistry and natural-product extraction (food, flavour, fragrance, nutraceutical, or ne-chemical sectors). Technical Competence Proficiency with Grignard, esterification, oxidation/reduction, enzymatic conversions, etc. Familiarity with pilot reactors (5-50 L), rotary evaporation, short-path distillation, chromatography. Ability to analyze and interpret spectral data (NMR, MS, IR) for structure confirmation. Working knowledge of Design of Experiments (DoE) and scale-up economics. 4. Desired Skills & Attributes Creative problem-solver focused on yield, purity, and cost optimization. Meticulous lab-notebook practice and data-integrity mindset. Ability to read and interpret patents (Google Patents, SciFinder, Reaxys). Clear written & verbal communication; able to present findings to non-chemists. Team-oriented and comfortable in a fast-paced, entrepreneurial environment. 5. Compensation & Benefits Salary Band: Rs. 5 -10 LPA (commensurate with experience). Annual performance bonus up to 15 %. Health & accident insurance, PF, and gratuity as per company policy. 6. Application Process Email the following to hrm@fnni.in with subject "Research Scientist- Organic Synthesis & Extraction: " 1. Updated CV (PDF) detailing synthesis/extraction projects. 2. Brief cover letter describing one significant process optimization you led. 3. Names & contact details of two professional references.

Qualifications and education requirement The prospective candidate should be a PhD/Post Doc in Biochemistry with a minimum of 5-8 years of research in academia or industry. Should have experience in enzyme characterization, enzyme kinetics and enzymatic conversions Roles and responsibilities Identification and development of processes for the purification of proteins/ enzymes from bacterial and / or yeast expression systems Development of strategies for maximizing the protein yield by solubilization of IB and refolding • Complete characterization of enzymes like activity, specific activity, pH optima, temperature optima, substrate loading, inhibition studies etc Determination of kinetic parameters Km, Vmax, rate of reaction etc Development of assays for different enzymes and optimization of analysis protocols Process development for production of different products using purified enzymes Identification of matrices for enzyme immobilization with reduced activity loss Perform operational stability studies of enzymes at different temperatures Development of lab scale process for packed bed conversion Essential attributes • Ability to work and liaison with multi functional teams • Acumen for leading and guiding peers and subordinates • Prior experience in carbohydrates would be desired • Passion for doing science and creating value

Executing chemicals reactions to synthesize required quantities of molecules/compounds as per customer specifications using efficient techniques. Set-up and execute reactions for synthesis Observing progress by using analytical technique Required Candidate profile Required Educational Qualification & Relevant experience M. Sc. (Chemistry) with 2-3 years of relevant experience

Industry Engineering Engineering Design R&D Quality Qualification M.Sc Key Skills Green Field Projects UPLC R&D Synthesis HPLC R&D Developed PDR Brownfield M.Sc Chemistry We are looking for a skilled R&D professional with 4 to 9 years of experience to join our team in the Employment Firms/Recruitment Services industry. The ideal candidate will have a strong background in synthesis and be able to work independently. Roles and Responsibility Develop and implement new methods for chemical synthesis. Conduct experiments and analyze data to optimize processes. Collaborate with cross-functional teams to achieve project goals. Design and develop new equipment and facilities for chemical synthesis. Troubleshoot issues and improve existing processes. Maintain accurate records of experiments and results. Job Requirements Strong knowledge of chemical synthesis and related techniques. Ability to work independently and as part of a team. Excellent problem-solving and analytical skills. Good communication and interpersonal skills. Ability to prioritize tasks and manage time effectively. Familiarity with laboratory equipment and safety protocols.

Job Summary: The R&D Chemist is responsible for conducting research, developing new chemical products, and improving existing formulations. This role involves working in a laboratory setting, performing experiments, analyzing data, and ensuring that products meet the required quality, safety, and performance standards. The R&D Chemist will collaborate with cross-functional teams to drive innovation and support the companys product development initiatives. Key Responsibilities: Research & Development: Conduct experiments to develop new chemical products or improve existing formulations. Perform research on the properties, composition, and reactions of substances to develop new processes or materials. Develop formulations for chemical products, ensuring that they meet performance, quality, and safety standards. Innovate new product ideas and applications based on market trends, customer needs, and emerging technologies. Analyze experimental data, interpret results, and make recommendations for further research or product optimization. Laboratory Work: Perform laboratory experiments using chemical techniques, including synthesis, purification, and characterization of chemical compounds. Maintain accurate records of experimental procedures, results, and observations in laboratory notebooks. Operate and maintain laboratory equipment, ensuring accurate and reliable results. Ensure that all laboratory work complies with safety regulations and standard operating procedures (SOPs). Product Testing & Analysis: Conduct tests to evaluate the performance, stability, and safety of chemical products. Use analytical techniques such as chromatography, spectroscopy, and titration to measure the chemical properties of substances. Interpret test results and adjust formulations to optimize product performance or resolve issues. Work closely with quality control and production teams to ensure that products meet required standards before commercialization. Collaboration & Cross-functional Support: Collaborate with the production, quality assurance, and regulatory teams to ensure that new formulations are scalable for manufacturing. Support the technical sales team by providing expertise on the chemical properties and applications of products. Liaise with suppliers and external research institutions to source materials or gather information for product development. Documentation & Reporting: Prepare detailed reports on research findings, product development progress, and experimental results. Document all research and development activities, ensuring that accurate records are maintained for regulatory and patent purposes. Present research findings and new product ideas to senior management and other departments. Assist in preparing technical documentation for new product launches or regulatory submissions. Regulatory Compliance & Safety: Ensure that all R&D activities comply with relevant regulatory standards and industry guidelines. Follow proper safety protocols in the laboratory, ensuring safe handling, storage, and disposal of chemicals. Stay up-to-date with changes in chemical regulations and industry trends to ensure that products are compliant. Continuous Improvement & Innovation: Stay informed about advancements in chemical research, materials science, and industry technologies. Participate in training and development programs to enhance knowledge of new methods, tools, and techniques. Propose new ideas and improvements for products, processes, and materials to keep the company at the forefront of innovation. Qualifications: Bachelors degree in Chemistry, Chemical Engineering, or a related field. 3+ years of experience in an R&D or laboratory environment, preferably in the chemical, pharmaceutical, or materials industries. Strong knowledge of chemical synthesis, formulations, and analytical methods. Experience with laboratory techniques such as chromatography, spectroscopy, and titration. Excellent problem-solving skills and attention to detail. Proficiency in using laboratory equipment and software for data analysis. Ability to work independently and as part of a team in a dynamic, fast-paced environment. Preferred Qualifications: Masters degree or PhD in Chemistry or related discipline. Experience in product development in industries such as coatings, adhesives, polymers, or specialty chemicals. Familiarity with regulatory standards (e.g., REACH, OSHA, GHS) and industry-specific guidelines. Knowledge of Good Laboratory Practices (GLP) and ISO standards. Strong project management and communication skills.

Role & responsibilities Conduct synthesis and process development experiments under the guidance of R&D scientists. Prepare reagents, carry out reactions, and monitor processes using TLC, HPLC, GC, NMR, and other tools. Record experimental procedures and results meticulously in lab notebooks and data sheets. Support scale-up trials from gram to kilogram scale; assist in transferring processes to pilot/manufacturing. Work on a range of chemistries including esters, surfactants, polymer intermediates, and fi ne chemicals. Assist in analytical method development, sample submissions, and customer evaluations. Maintain lab hygiene, safety protocols, and raw material inventory. Preferred candidate profile B.Sc. / M.Sc. in Organic Chemistry, Applied Chemistry, or Chemical Sciences. 13 years of hands-on lab experience in a chemical or specialty chemical R&D setup. Exposure to synthesis, reaction monitoring, and basic analytical techniques. Basic understanding of scale-up challenges and process parameters. Good documentation, problem-solving, and communication skills.

Key Responsibilities Conduct synthesis and process development experiments under the guidance of R&D scientists. Health insurance Provident fund

Walk-In Drive For API Research & Development(R&D)- Venue Details : MSN Laboratories Pvt. Ltd, R&D Centre, Pashamylaram (V), Patancheru (M), Sangareddy (D.t), Telangana on Friday 27-06-2025 . Department : API R&D Designation : Executive / Sr. Executive Experience : 1- 7 Years Qualification : M.Sc. Organic Chemistry Work Location : MSN R&D Center, Pashamylaram, Hyderabad Work Location : MSN R&D Center, Pashamylaram, Hyderabad Interview Venue Details : Venue Details : MSN Laboratories Pvt. Ltd, R&D Centre, Pashamylaram (V), Patancheru (M), Sangareddy (D.t), Telangana on Friday 27-06-2025 .

Develop the scientific & strategic direction of the synthesis research business, overseeing drug discovery initiatives, managing research teams, ensuring the effective administration & growth. Required Candidate profile Ph.D. in Chemistry with 12+ years in CRO/ process development/ chemical synthesis with flair of senior research leadership role would be an ideal fit. Willing to work at the lab and be a mentor. Perks and benefits Best of CTC, additional perks and benefits

Role & responsibilities Expertise in carrying out Multi-step synthesis of organic molecules from milligram to multi-gram scales and their characterization. Responsible for the development efficient synthetic process, which leads to better yields and quality of the product, with less cycle time and cost. Capturing proper learning of the project & would be responsible for maintaining the confidentiality of the project as per the IPR guidelines. Scaling up of process and technology transfer from lab to plant and trouble shooting at the time of scale up. Interpretation of analytical reports like HPLC, GC, NMR, LCMS, IR, GCMS. Knowledge of designing route of synthesis for target molecule. Carried out experiments in laboratory and optimize process in terms of Regulatory Affairs (RA), Safety, cost and time effectiveness. Strong knowledge on process validation in laboratory and demonstration in plants. Adept at preparing documents like Technology transfer document (TTD), Process development report (PDR), presentations and reports for review meetings. Process validation and optimization with QBD. Preparing documents like Solubility chart, Material balance, Green card, Hold time study, Details of process, MSD. Literature search .through Sci-finder and Reaxys Ability to handle linear and parallel multi-step organic synthesis Experienced with purification techniques like thin layer & column chromatography, Crystallization and distillations. Structural elucidation through NMR (1H, 13C), IR, Mass (LC/MS, GC/MS). Good Co ordination with Cross functional teams as well as team mates. Accurate record keeping in laboratory notebook (LNB) and (ELN).

Position: Senior Manager - Peptide Production Grade: G9B / G9A Job Location: Ahmednagar Qualification: M.Sc. (Chemistry) / B.E. (Chemical) / B.Tech (Chemical) Experience: 13-18 yrs experience in Peptide API plant Job Profile 1. To plan and execute peptide manufacturing activities as per the schedule and Budget by optimum utilization of plant capacity 2. To ensure the sustainable quality production with optimum utilization of plant capacity. 3. Monitoring and reduction in process TRT, Cleaning TRT, number of preps per batch on Prep HPLC, Improve yields. Improve the process of Synthesis & Analytical Section. 4. Co-ordinate with Purchase, Planning department to deliver the goods in time. 5. To ensure every day interaction with each department for smooth functioning 6. Compliance of waste water disposal as per IN-HOUSE policy 7. To ensure grooming of disciplined workforce and staff to meet the planned growth charts. 8. Developing different innovative practices to increase productivities and up gradation of work culture. 9. To maintain Good Documentation Practices and Good Laboratory Practices 10. Review of batch process record, Standard Operating procedure and cGMP documents 11. Investigation of Deviation, Change Control & OOS 12. Implementation & follow all safety instruction & practices

Synthetic experience from Gram to kilogram scale Experience in handling moisture and light sensitive reagents API’s Analysis and characterization of molecule using techniques Structural interpretation of intermediates and finished products

Roles and Responsibilities Ensure compliance with GMP guidelines during API manufacturing processes. Monitor equipment performance and troubleshoot issues related to piping systems. Maintain accurate records of production data, quality control tests, and inventory management. Experience needed: Production - 0 -4 years Engineering production-6-8 yrs

Role & responsibilities Preferred candidate profile •Process Development • R&D Chemist • Process Chemistry • Process Optimization • Chemical Synthesis • Route Scouting • Reaction Mechanism • Lab Autoclave -Hydrogenation, Reduction, Hydrolysis, Methylation, Esterification, Kolbe-smith Carboxylation, Distillation, Acidification and high-Pressure reaction.