Assistant Manager-Medicinal Chemistry

Job Description

Job Summary: As a Medicinal Chemist, you will play a pivotal role in the design, synthesis, and optimization of novel drug candidates. This role requires scientific expertise, problem-solving skills, and hands-on laboratory experience to drive drug discovery projects from hit identification to lead optimization and preclinical development. You will work closely with cross-functional teams to develop innovative therapeutics that address unmet medical needs. Responsibilities: Design and synthesize novel small molecules to target specific disease indications. Planning and implementation of novel approach to drug discovery and development independently or in collaboration. Apply Structure-Activity Relationships (SAR) and Structure-Property Relationships (SPR) to optimize potency, selectivity, and pharmacokinetic properties. Collaborate with computational chemists, biologists, and pharmacologists to design and prioritize new chemical entities for synthesis and biological evaluation. Perform literature searches and analyze scientific literature to identify and implement new synthetic methodologies and technologies. Contribute to the preparation of patent applications, technical reports, and scientific publications. Use computational models and simulations to predict the behavior of new drugs and to guide the design of new compounds. Stay updated with emerging trends in AI-driven drug discovery and medicinal chemistry innovations. Understand Structure Activity Relationships and Structure Property Relationships of various projects. Qualifications and Skills: Ph.D. in Organic Chemistry, or related field. 10-13 years of industry experience in Life Sciences, R&D, CRO, biotech, or pharmaceutical settings. Strong background in synthetic organic chemistry, medicinal chemistry, and chemical biology. Proficiency in modern synthetic methods, purification techniques, and analytical instrumentation (e.g., NMR, LC-MS, HPLC). Demonstrated success in lead optimization and preclinical drug discovery. Familiarity with pharmaceutical industry practices and regulatory frameworks. Knowledge of AI-driven drug discovery methodologies is an advantage. Excellent problem-solving skills, scientific creativity, and a passion for innovation. Strong communication and interpersonal skills, with the ability to collaborate in a multidisciplinary environment.